- Pragmatic RCT comparing management of hypertension using routine (including ‘usual’ dialysis unit BP in in-centre haemodialysis patients) BP, HBPM and ABPM in dialysis patients.
- Pragmatic RCT in both haemodialysis and peritoneal dialysis to determine optimal BP target ranges, preferably utilising standardised office BP or home BP monitoring as the primary method for measuring BP
- RCT of multiple lifestyle interventions (including dietary salt and fluid reduction, exercise and psychosocial support for medication adherence) on BP and symptomatic IDH in people on dialysis.
- An implementation or hybrid effectiveness-implementation study of protocolised fluid volume management to improve CV outcomes in people receiving haemodialysis.
- RCT to determine whether routine evening/night-time dosing of antihypertensive medication reduces incidence of symptomatic intra-dialytic hypotension.
- RCT to determine effectiveness of midodrine and/or L-carnitine in preventing symptomatic IDH and reducing hospitalisations, and whether these treatments are well tolerated and safe.
- RCT in CYP on dialysis to determine whether those in whom BP is targeted to <90th centile have a lower risk of LVH compared with those in whom BP is permitted ≥90th centile.
- Study in CYP on dialysis to determine whether HBPM values correlate with data from ABPM assessment.
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