UK Clinical Practice Guidelines for Kidney Disease

Since 1995, we have provided evidence-based guidelines to support the management of kidney disease, aiming to improve care and outcomes for patients. Our individual guidelines are developed independently and free from external funding. They help healthcare professionals deliver consistent, high-quality practice across the UK. 

Developed by the UK Kidney Association with expert multi-professional input and evidence review.

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This Interactive Guidelines Website was funded by CSL Vifor through an independent grant, and it has been independently developed and is managed by the UK Kidney Association.

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Since the publication of the first UKKA clinical practice guideline for the use of SGLT 2 inhibition in adults with kidney disease in October 2021, two large and highly relevant clinical trials have been published (DELIVER and EMPA KIDNEY). In light of this new evidence, the 2021 guidelines have been reviewed and updated by the original working group members. The structure of the 2021 guideline which provided recommendations for use for people with diabetes (section 2) and without diabetes (section 3) separately has been retained.

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Haemodialysis continues to expand in the UK, with over 25,000 patients now being treated, representing a 10% increase since the publication of the previous Renal Association guideline for haemodialysis. In addition, the patient group continues to develop: the typical patient is now 67 years old with a median history of 3.2 years on renal replacement therapy.

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An update of the UKKA Hyperkalaemia Guideline (2020) was prompted following enquiries related to the administration of Calcium Gluconate and to provide new guidance related to the use of oral potassium binders and blood glucose monitoring. Therefore, the main changes to treatment recommendations are within the Hospital Section of this update.

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About our guidelines

The Clinical Practice Guidelines Committee, established by the UK Kidney Association in 1995, develops evidence-based guidelines for the care of people with kidney disease. The committee also advises on the data collected by the UK Renal Registry to support up-to-date, safe clinical practice, with the aim of improving outcomes for patients.

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