Dialysability of blood pressure lowering medication
Beta Blockers
| Medication | Dialysed in HDF/High Flux | Dialysed in PD | Half life (hrs) | Half life in ESRF (hrs) |
|---|---|---|---|---|
| Atenolol | Dialysed | Not dialysed | 6–7 | 15–35 |
| Bisoprolol | Dialysed | Not dialysed | 9–12 | 18–24 |
| Carvedilol | Not dialysed | Unlikely | 6–10 | Unchanged |
| Labetalol | Unknown | Not dialysed | 4–8 | Unchanged |
| Metoprolol | Dialysed | Not dialysed | 1–9 | Unchanged |
| Propranolol | Unknown | Not dialysed | 2–6 | Unchanged |
Calcium Channel Blockers
Calcium channel blockers
| Medication | Dialysed in HDF/High Flux | Dialysed in PD | Half life (hrs) | Half life in ESRF (hrs) |
|---|---|---|---|---|
| Amlodipine | Unlikely | Not dialysed | 35–50 | 50 |
| Diltiazem | Not dialysed | Not dialysed | 2–11; SR 5–8 | Unchanged |
| Felodipine | Not dialysed | Not dialysed | 24 | Unchanged |
| Lacidipine | Unknown | Unknown | 13–19 | Unknown |
| Lercanidipine | Unknown | Unlikely | 8–10 | Increased |
| Nicardipine | Unknown | Unlikely | 8.6 | Unchanged |
| Nifedipine | Unknown | Not dialysed | 1.4–11 (depends on formulation) | Unchanged |
| Verapamil | Unknown | Not dialysed | 4.5–12 | Increased |
ACE Inhibitors
| Medication | Dialysed in HDF/High Flux | Dialysed in PD | Half life (hrs) | Half life in ESRF (hrs) |
|---|---|---|---|---|
| Captopril | Dialysed | Not dialysed | 2–3 | 21–32 |
| Enalapril | Dialysed | Dialysed | 11 | 34–60 |
| Fosinapril | Unlikely | Not dialysed | 11.5–14 | 14–32 |
| Lisinopril | Dialysed | Unknown | 12 | 40–50 |
| Perindopril | Dialysed | Unknown | 1 | 27 |
| Quinapril | Dialysed | Not dialysed | 1 | 12–14 |
| Ramipril | Dialysed | Unknown | 13–17 | Increased |
MRAs
MRAs
| Medication | Dialysed in HDF/High Flux | Dialysed in PD | Half life (hrs) | Half life in ESRF (hrs) |
|---|---|---|---|---|
| Eplerenone | Unknown | Unknown | 3–6 | Unknown |
| Spironolactone | Unknown | Not dialysed | 1.3–1.4 | Unchanged |
ARBs
| Medication | Dialysed in HDF/High Flux | Dialysed in PD | Half life (hrs) | Half life in ESRF (hrs) |
|---|---|---|---|---|
| Azilsartan | Not dialysed | Not dialysed | 11 | 15–18 |
| Candesartan | Not dialysed | Unlikely | 9 | 18 |
| Irbesartan | Unknown | Not dialysed | 11–15 | Unchanged |
| Losartan | Not dialysed | Not dialysed | 1.5–2.5 | 4–6 |
| Olmesartan | Unlikely | Not dialysed | 10–15 | 36 |
| Telmisartan | Unknown | Not dialysed | 24 | Unchanged |
| Valsartan | Unknown | Not dialysed | 5–9 | Unchanged |